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Therefore, prolonged exposure to low mycotoxins concentrations activates metabolic feedback between different tissues, affecting, finally, the whole metabolic homeostasis in a fragile condition

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Jan 2004;63(1):7-11

AMP-activated protein kinase phosphorylation of endothelial NO synthase

Each mechanism of dysfunction at the pre-synaptic, post-synaptic, and peri-synaptic level offers itself as a target for intervention to improve stabilization, junctional signaling, and synapse integrity [213], potentially even before symptomatic weakness in those with genetic susceptibilities