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4 The bodys metabolic rate increases during high-intensity exercise, increasing the demand for oxygen to produce muscle energy

MiR-136 modulates glioma cell sensitivity to temozolomide by targeting astrocyte elevated gene-1

AMP, Adenosine monophosphate

Besides, roFPs under physiological conditions are only sensitive to oxidative stress but not to any reductive stress because they completely transition to a fully reduced state once in the cytosol

The former mechanism is preferred because RS scavengers can be consumed during the reaction and may generate toxic radicals derived from the chelators (Halliwell and Gutteridge, 2015)