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Through PPI network and MCODE clustering analysis, key lipid metabolism genes were identified

Soy M, Keser G, Atagndz P, Tabak F, Atagndz I, Kayhan S

For example, VLDL and HDL are assembled in the endoplasmic reticulum of liver, and their level is tightly regulated by LDLR and SR-BI mediated uptake, along with apolipoproteins such as apoB100 which, together, orchestrate lipid trafficking between peripheral tissues and the liver to control lipid and cholesterol homeostasis 9,122,123,124

[180]demonstrated that in MASLD, compromised GSH-GPX4 axis and decreased lipophilic antioxidants enhance ferroptosis, resulting in hepatic mitochondrial dysfunction

Most of the 1,2-dibromoethane was accounted for