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Hypoxia-induced pulmonary hypertension-Utilizing experiments of nature

mTORC1 signaling induces genes involved in amino acid synthesis, transport, and tRNA charging through ATF4 activation To validate and expand the findings from the RNA-seq analysis, a Nanostring codeset was designed to simultaneously quantify transcripts of genes involved in the enriched processes above (see methods)

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The clearance of ROS in the human body mainly depends on GSH, which is mainly composed of small molecular peptides composed of glutamate (Glu), cysteine (Cys), and glycine (Gly) (Xiao and Meierhofer, 2019)

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