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Caravia, University of Texas Southwestern Medical Center, United States Reviewed by Shogo Sato, Texas A and M University, United States Thomas Mortimer, Institute for Research in Biomedicine, Spain Updates Copyright 2025 Garca Cobarro, Ignez Soares, Kutsenko and Tomas-Loba

By far the biggest contributing factor to carnosine synthesis is the dose and duration of beta-alanine supplementation, as studies have shown that doubling the daily dose of beta-alanine results in about double the amount of carnosine synthesized (and halves the time to get to the same increase) (Church et al., 2017