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The 1998 characterization reported that ipamorelin released growth hormone with a selectivity profile in which those other hormones were not significantly elevated even well above the dose producing half-maximal GH release, evidence of signal selectivity at the GHS-R1a receptor

Side effects by dose level In clinical trials, nausea affected approximately 20% of participants, with most episodes being mild to moderate and resolving within the first few weeks at each dose level