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Notably, acetylcarnitine can act as an acetyl donor [37], supporting the acetylation process of cells through the shuttle mechanism of acetylcarnitine in the absence of conventional acetyl-CoA synthetase enzymes such as ATP-citrate lyase (ACLY) and acyl-CoA synthetase short chain 2 (ACSS2) [38]

NC was measured at mid-neck height, between the mid-cervical spine and mid-anterior neck while sitting with a straight back, all to the nearest 0.1 cm

doi: 10.1371/journal.pone.0179124 149 BlombergJRizwanMBhlin-WienerAElfaitouriAJulinPZachrissonOet al

[PubMed: 11116058] 341

(2017) observed that TMAO treatment promoted monocyte adhesion through upregulation of vascular cell adhesion molecule-1 (VCAM-1) but not the other adhesion molecules (i.e., intercellular adhesion molecule-1 (ICAM-1) and E-selectin) expression in human umbilical vein endothelial cells in vitro