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As such, this review highlights the urgent need for clinical trials targeting antiangiogenic therapies in neurodegenerative diseases, because without robust data from clinical studies, the efficacy and safety of such interventions remain speculative

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Sprained thumbs are also common in skiers and in athletes who participate in sports that involve catching and throwing a ball, such as football, baseball, softball, and basketball

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Abrupt discontinuation should be avoided because it may precipitate rebound sympathetic activation, catecholamine surge, and severe rebound hypertension