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Modulatory effects of silibinin in various cell signaling pathways against liver disorders and cancer - a comprehensive review

doi: 10.3389/fnut.2025.1678150 Received 04 August 2025 Accepted 02 October 2025 Published 06 November 2025 Volume 12 - 2025 Edited by Hengyi Xu, Nanchang University, China Reviewed by Jashbhai B

Abstract It appears that the marked increase in the rate of autism, asthma, and attention deficit with hyperactivity throughout much of the world may be largely caused by the marked increase in the use of acetaminophen in genetically and/or metabolically susceptible children, and the use of acetaminophen by pregnant women

[DOI] [PMC free article] [PubMed] [Google Scholar] 139.Jordan A.J., Manor B., Iloputaife I., Habtemariam D.A., Bean J.F., Sorond F.A., Lipsitz L.A

The URA3 , GFP-tADH1 and HS fragments for GSH1 were ligated between the Sac I and Sal I sites of pRS315 (ATCC) via Gibson assembly using a HiFi DNA assembly cloning kit (New England Biolabs, NEB) according to the manufacturers instructions