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Insect glutathione-S-transferase: A predictor of allelochemical and oxidative stress

[8] Intravenous lysine is contraindicated in patients with known hypersensitivity to lysine or any formulation component and should be avoided in individuals with severe hepatic insufficiency who cannot adequately metabolize cationic amino acids, as such impairment may lead to heightened plasma ammonia and encephalopathic risk

Although oxidative stress and iron accumulation are hallmark features of FRDA, it is unclear whether iron accumulation is a cause or a consequence of the disease [15]

The rat GCLM promoter also has a functional ARE element (295 to 285) (Yang et al., 2005b)

Likewise, tyrosine phosphatase SHP2 could dephosphorylate STAT3 and suppress the induction of C/EBP and C/EBP, ultimately blocking adipogenic differentiation [53]