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At the infection site, the low intracellular calcium concentration triggers the release mechanism of the nanocrystals, allowing the drug to be directly released inside the cells, thereby avoiding systemic tissue damage caused by Amphotericin B (Boulware et al., 2023)

This guideline was developed by the Guidelines and Protocols Advisory Committee in collaboration with the Provincial Laboratory Medicine Services, and adopted under the Medical Services Act and the Laboratory Services Act

normal control group treated with AST

Therefore, MSCs and their exosomes may be potential pyroptosis inhibitors

The tower domain of LSD1 and its interactions with CoREST may play a mechanistic role in this phenomenon, given that catalytic LSD1 inhibition does not phenocopy scaffolding LSD1 inhibition