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This optimum pH of the PEI-f-AuNP@Van probe is likely related to the conformation of PEI and the pKa of the tertiary amine ( 2+ must be optimally coordinated with nitrogen atoms in PEI in its N-tetrahedral form, giving rise to highest sensitivity and selectivity for the probe ( FIGURE 7 3.7 Real sample analysis Pond water was used to evaluate the performance of PEI-f-Au-NP@Van for detecting Hg 2+

These results demonstrate that intertumoral EV transfer occurs in vivo

More importantly, interfering with tumor metabolism to control tumor progression is a very promising approach in cancer treatment, although it is full of challenges

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