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Mutations in the corresponding GATA-1 gene are linked to many human diseases, including acute megakaryoblastic leukemia in Down Syndrome children (DS-AMKL), X-linked thrombocytopenia, and gray platelet syndrome (6-9)

Ligibel JA, Bohlke KAC (2022) Exercise, diet, and weight management during cancer treatment: ASCO guideline summary and Q&a

Currently, nucleoside analogs used to treat hepatitis B patients can inhibit virus replication but have poor immune-modulating capabilities, thus cannot completely suppress the liver damage caused by the subsequent development of hepatitis B

Common side effects include mild soreness at the injection site, headache and dizziness, but these are temporary

Similar observations were made in transgenic embryos that are incapable of de novo GSH biosynthesis (Shi et al., 2000)