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T-cell apoptosis in autoimmune diseases: termination of inflammation in the nervous system and other sites with specialized immune-defense mechanisms

Therefore, even in the presence of higher PGC-1 gene expression as a result of mTOR hyperactivity during early AMD stages, a reduction in PGC-1 activity in later stages could ultimately affect mitochondrial turnover and biogenesis causing increased ROS production and cell death

Because the skin is the protective barrier to the environment, it can receive direct oxidative damage in the epidermis

Handa H, Cheong JW, Onishi Y, Iida H, Kobayashi Y, Kim HJ, Chiou TJ, Izutsu K, Tsukurov O, Zhou X, et al

Therefore, finding effective and low-toxic active substances from traditional Chinese medicines for treating rheumatoid diseases, or developing more efficient and quality-controlled drugs based on them, is also an important development direction for treating RA at present and in the future