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The GFE includes a brief health assessment conducted under the supervision of a licensed medical provider

However, findings in elite athletes remain inconsistent

10.1021/acs.jmedchem.5b01641 J Med Chem

doi:10.1186/s13023-022-02179-y

Metformin also seems to alter the gut microbiome, but it is unclear whether this alteration reduces body-wide inflammation a major driver of aging which probiotics and omega-3 fatty acids were shown to do in the same study