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Statistical Analysis Statistical analysis of the experimental data was performed using GraphPad Prism software (Version 8.02), and the data are represented as the mean SEM

The inhibition of GPX4 by (1S,3R)-RSL3 decreased the viability of drug-resistant cancer cells and reduced tumor size in mouse models

Cultures were maintained at 262 C under a 16/8 h (dark/light) photoperiod, with a light intensity of 40 mol m -2 s -1 provided by cool white fluorescent lights (Philips India Ltd., India)