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Treatment for ACD consists of avoiding trigger factors and using topical corticosteroids, calcineurin inhibitors (tacrolimus and pimecrolimus), and systemic immunosuppressive agents for severe cases [110]

DNA Damage (Mutation / Strand Break) Radicals cause base modifications and single or double strand breaks

Nature 411, 595599

A detailed discussion of these scores is outside the remit of this article

2 Fluoroquinolones: The fluoroquinolones ofloxacin, ciprofloxacin, and levofloxacin should only be used as first-line therapy in communities with high rates of TMP-SMX resistance (10%) to E coli since these agents have other important indications