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Indeed, hypoxia contributes to high levels of oxidative stress [42], important in the context of depression, highlighted in this manuscript

By downregulating NFE2L2 and inhibiting the nuclear receptor subfamily 2 group F member 6/KEAP1 signaling pathway, apatinib has been demonstrated to induce ferroptosis in glioma cells

Koike, S

Vitamin B3 (Niacin) Niacin, especially in high doses, can lead to gastrointestinal upset, including nausea and abdominal pain

This article systematically reviews the progress of photodynamic therapy, the mechanism of action of light-activated prodrugs, the coupling strategies between prodrugs and photosensitizers (including covalent bonds and non-covalent bonds), and the clinical translation challenges of light-activated prodrug systems