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Christen F, Desrosiers V, Dupont-Cyr BA, Vandenberg GW, Le Franois NR, Tardif JC, et al

[DOI] [PubMed] [Google Scholar] Xu Y

adjusted to optical density at 600 nanometres (OD 600 ) of 1.5

This irritation can trigger excess melanin activity, leading to darker patches after treatment instead of improvement

However, more recent evidence suggests that these vascular changes are not the cause of migraine, but rather an epiphenomenon that accompanies the pain (Rizzoli 2012)