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One of the most common and effective treatments for melanoma is called a "wide excision." This surgery removes the melanoma along with a healthy border of skin around it

[PUBMED Abstract] Leitao MM, Cheng X, Hamilton AL, et al.: Gynecologic Cancer InterGroup (GCIG) consensus review for vulvovaginal melanomas

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Regarding the expression of mucin core proteins, vulvar Paget disease may arise from ectopic MUC5AC-positive cells originating from Bartholin or some other unidentified glands, while the unique expression of MUC2 in perianal Paget disease indicates that its origin from colorectal mucosa differs from that in the vulva