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However, their modest efficacy in solid tumors, coupled with metabolic side effects such as insulin resistance and immunosuppression, highlights the need for more selective and context-dependent modulators

Li M, Zhang R, Xin M, Xu Y, Liu S, Yu B, Zhang B, Liu J

Neurodevelopmental functions of O-GlcNAcylation in the brain In the complex milieu of neural development, O-GlcNAcylation assumes a critical regulatory role

Absorbance was calculated at an optical density (OD) of 450630 nm after an additional 2 h of CCK-8 incubation at 37C using the microplate reader (Thermo Labsystems, Finland)

In critical situations, the reduction in plasma glutamine concentration affects the redox state and the metabolism of cells of the immune system, resulting in compromised immune response contributing to the development of sepsis