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Siegel MP, Kruse SE, Percival JM, Goh J, White CC, Hopkins HC, Kavanagh TJ, Szeto HH, Rabinovitch PS, Marcinek DJ

For all constructs, except for the non-binding control NAPstarC and NAPstar4, we observed an NADPH concentration-dependent change in the TS/mC fluorescence emission ratio ( Figure 1C )

M.SmithW

Sotomayor, MD, director of the GW Cancer Center and professor of medicine at the GW School of Medicine and Health Sciences

Moreover, by immunostaining and expression analysis of primary endothelial cells, we observed reduced protein and mRNA abundance of the tight junction protein occludin, and reduced Abcb1a mRNA of the ABCB1 (P-glycoprotein) efflux transporter, likely explaining the decreased tightness of the barrier in vitro (Fig