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Lipid nanoparticles as drug/gene delivery systems to the retina

Additionally, this pathway can inhibit activated protein kinase C and reduce coenzyme II (nicotinamide adenine dinucleotide phosphate, NADPH) activity, alleviate ER stress and lipid accumulation (Jin et al., 2021), scavenge accumulated oxidative products, and reverse oxidative stress damage in nerve cells, thereby delaying or preventing the progression of VaD