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Area covered This review explores the role of pharmacokinetics in the development and optimization of DDS, with an emphasis on basic compartmental models and physiologically-based pharmacokinetic (PBPK) models that are essential for describing drug ADME in the body

doi: 10.1016/S0278-5846(96)00103-0, PMID: [DOI] [PubMed] [Google Scholar] 27.Richie JP, Jr, Nichenametla S, Neidig W, Calcagnotto A, Haley JS, Schell TD, et al

Mitochondrial iron at the crossroads with human diseases Given the diverse and vital roles of mitochondrial iron, it is not surprising that imbalances can have pathological consequences