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Polysaccharides from Polygonatum cyrtonema hua prevent post-traumatic stress disorder behaviors in mice: mechanisms from the perspective of synaptic injury, oxidative stress, and neuroinflammation

If the FDA accepts the carve-out, the generic can launch before the method-of-use patent expires, generating revenue on the unpatented indications while the brand retains market protection for the patented one

The interaction of UCB with microglia initially affects defensive processes involved with the expression nuclear factor kappa B (NF-B) and of mitogen-activated protein kinases (MAPKs) as well as enhanced phagocytosis and the subsequent generation of pro-inflammatory cytokines

Broadly neutralizing antibodies target the coronavirus fusion peptide

Multidimensional analysis and therapeutic development using patient iPSCderived disease models of Wolfram syndrome