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Permeation across this protective barrier is actively mediated by the organic cation/carnitine transporter known as OCTN2 (SLC22A5)

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Trotti, Lynn Marie, and Isabelle Arnulf

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Low-dose rapamycin, by inhibiting mTOR activity, reduces the expression of pro-inflammatory proteins and stifles mTOR-driven aging (Mizumura and Gon 2021)

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