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There are two explanations for the increased relative abundance of oral bacteria in feces: one is that oral bacteria invade and expand within the gut ecosystem (the Expansion hypothesis), the other is that the relative increase in oral bacteria and signify the depletion of other gut bacteria (the Marker hypothesis) 33

Chen X, Wu W, Gong B, Hou L, Dong X, Xu C, Zhao R, Yu Q, Zhou Z, Huang S, Chen L

Nutrition and bi-partite metabolism of intracellular pathogens

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Specifically, treated patients improved by ~ 5.8 points on the UPDRS-III (motor) versus ~ 2.7 points in controls, with benefits sustained for at least a year [175]