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Mol Cell Endocrinol 401:213220

The substitution of a relatively small side chain residue in the NaAtm1 cavity creates extra space and shifts the binding site towards the apex, which in turn likely allows for more plasticity when interacting with GSH and related compounds (Fig

For anti-oxidant defense in the GI tract, a gastric hormone, ghrelin, mainly produced in gastric mucosa, reduces the inflammation processes by inhibiting inflammatory cytokine expression and attenuating oxidative stress [24]