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Three-dimensional regeneration of patient-derived intestinal organoid epithelium in a physiodynamic mucosal interface-on-a-chip

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Autophagy is a highly conserved cellular pathway involving the formation of autophagosomes to deliver cargoes, including long-lived proteins, protein aggregates, organelles, and infected viruses or bacteria, to lysosomes for degradation 13,14,15

Copper entering the portal circulation bound to these plasma proteins is transported to organs and tissues