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Overdosing can lead to undesired side effects, while underdosing may reduce efficacy

doi: 10.1038/onc.2008.398 339 JunH-OKimYKwonY-WHongS-SKimK-WShinJet al

The transcription factor p53 is a tumor suppressor, and mutations are often identified in lung SCC (14)

Copper toxicity Though its unlikely, copper peptide skin care products may lead to potential copper toxicity if not used as directed by the manufacturer (or if multiple copper-containing products are used together)

Peer review Peer review information Nature Reviews Nephrology thanks Daniel Muruve and the other, anonymous, reviewer(s) for their contribution to the peer review of this work