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[DOI] [PMC free article] [PubMed] [Google Scholar] 101.Hansen G, Victor R, Engeldinger E, Schweitzer C

Where CJC-1295/Ipamorelin works by elevating GH to drive IGF-1 production in the liver, IGF-1 LR3 acts directly at the muscle tissue level binding IGF-1 receptors on muscle cells to stimulate protein synthesis, satellite cell activation, and muscle hypertrophy independently of the GH axis