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The comet assay has been a reliable tool or indicators for damages of nuclear DNA and its quantitative pattern directly corroborating intensity of stresses

[2] This increase in MMP-2 was also accompanied by a rise in MMP-2 mRNA levels, indicating that GHK-Cu potentially enhances MMP-2 expression at the transcriptional level

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Franois C, Hauser RA, Aballa S, Dorey J, Kharitonova E, Hewitt LA

The ability to deliver high local IGF-1 concentrations without systemic exposure could be advantageous in rehabilitation medicine, though clinical validation requires further research