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The method of claim 56, wherein the set of variant nucleic acids is generated by performing amplification reactions on the nucleic acid of step (a) using the set of oligonucleotides to generate a set of variant nucleic acids encoding nineteen amino acid substitution variants at a single amino acid residue of the antigen-binding polypeptide

Nassar M

(179) used transcriptome analysis to reveal mitochondrial shrinkage, lipid peroxidation, ROS accumulation, and increased PUFA levels in Cyp4v3 (homolog of human CYP4V2) knockout mouse RPE cells

In contrast, when cells had been pretreated with BSO before AX addition, a drastic decrease in both GSH and the GSH/GSSG ratio was observed compared to both control and AX-treated cells ( Figure 7A )

Their work complements the work of student advising