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clinicians should monitor for gastrointestinal cramping or bradycardia in co-treated patients

The FDA granted fast track designation (FDA 2010) for pixantrone in patients who had previously been treated with two or more lines of therapy for relapsed or refractory aggressive NHL (Mukherji 2009)

Given that an improvement in swimming speed reflects an increase in muscle strength, we administered drugs to the F1 larvae and assessed their swimming speed using DanioVision