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Description

By localizing therapy to sites of neurodegeneration, these strategies mitigate peripheral side effects and circumvent BBB limitations

It is dosed at 1 mg to 2 mg daily, subcutaneously

364 In an APP/PS1 mouse model of AD that carries human AD-linked mutations in APP and PSEN 1 genes, UA restored neuronal mitophagy, ameliorated cognitive decline, reduced A pathology, and mitigated neuroinflammation