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A Phase I, Randomised, Double-Blind, Placebo-Controlled, Single Ascending Dose, Multiple Dose, and Food Effect Trial of the Safety, Tolerability and Pharmacokinetics of Highly Purified Cannabidiol in Healthy Subjects

The AsA pool directly reduced MDHA by ferredoxin at photosystem I (PSI), Monodehydroascorbate reductase (MDHAR), and dehydroascorbate (DHA) reduction via GSH-dependent dehydroascorbate reductase (DHAR) activity

Studies suggest that this suppression of GSH by BSO may be a rather efficient strategy in cancer therapy since, during this process, there is an increase in the sensitivity of cells to ionizing radiation and to cytostatic drugs, making them more susceptible to treatment