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Enzyme deficiencies, particularly in diamine oxidase (DAO) and histamine-N-methyltransferase (HNMT), are also key contributors to histamine intolerance

In addition to the well-established benefits of CR, multiple studies have demonstrated that during intermittent fasting (IF), neurons undergo an adaptive response mediated by elevated BDNF levels, which enhance neuronal resilience and plasticity in response to metabolic stress 40,41,42

In fact, astrocytes play a key role in glutathione metabolism in your brain.[xiii] Glutathione helps recycle other antioxidants

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