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Exp Biol Med (Maywood) 2002;227(3):214-22

Another pivotal endocrine abnormality involves altered gonadotropin secretion, particularly an increased luteinizing hormone (LH) to follicle-stimulating hormone (FSH) ratio

Self-reported 5 UK units exceeded all devices sensitivity

Pale brown to black lentigines are the most common feature and are present in 70% to 80% of affected individuals

Clinicians and other ancillary health workers should be properly trained to have a high index of suspicion of thiamine deficiency in situations of unbalanced nutrition that has lasted for 2 to 3 weeks to avoid misdiagnosis of the life threatening WE or irreversible brain damage caused by KS