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In an experimental autoimmune encephalomyelitis (EAE) model of MS, a high-fiber diet that boosts SCFA production expanded Foxp3 + Tregs, strengthened the gut barrier, and reduced CNS inflammation and disease severity [41]

Neuroreport 11:19291932 Gu H (2013) Stem cell-derived neurons for the treatment of neurodegenerative diseases

Dissecting these properties against SARS-CoV-2 is likely necessary for defining metrics of immunity that will inform the design of vaccines and therapeutics and improve clinical management