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Dual inhibition of TGF-beta and PD-L1: a novel approach to cancer treatment

Psoriasis and Eczema

Psychopharmacologia , 10 , 184188

10.1038/s41467-020-20513-5 36

Mechanistic studies suggest that Rg1 reduces caspase cascade activation by modulating apoptosis-related proteins (e.g., upregulating Bcl-2 and suppressing Bax and p-c-Jun expression)