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Furthermore, downregulation of nuclear factor E2-related factor 2 (Nrf2) leads to reduced GPX4 expression, thereby intensifying ferroptosis (Ni et al., 2020

Low glutathione S-transferase P1 levels are associated with higher mortality in COVID-19 patients, and high levels of glutathione S-transferase P1 possibly offer protection for cellular redox reactions in severe COVID-19 infection, preventing deterioration especially in patients with co-morbidities like diabetes (Kumar D.S

Lindermayr, C., Sell, S., Mller, B., Leister, D

equiseti AUMC 15585 clustered into a well-supported F

Beyond the demonstration that pharmacologic blockade of IGF-1R signaling can favorably impact lifespan, these data also provide new insights into temporal and metabolic aspects regarding this pathway and aging