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FDA (2023) New Dietary Ingredient (NDI) Notification process

Phil Trans Roy Soc Lond 1810;100:22330

Though NAD IV therapy achieved celebrity status in recent years, its actually been used in clinical settings since the 1960s, when doctors in substance abuse treatment facilities started administering it to assist with withdrawals 3

En el estudio intravenoso humano de pequeo tamao (n=6), el DSIP se report como bien tolerado , sin efectos adversos psicolgicos, fisiolgicos ni bioqumicos observados (PMID 6895513)