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GSH is a constituent of blood plasma

Local (and systemic) estradiol can stimulate lesion production of PGE2, which can activate pain fibers, enhance neuronal invasion of lesions by stimulating production of NGF and other neurotrophins, and promote sprouting of nociceptors that contribute persistent inflammatory pain and inhibit neuronal apoptosis

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One peptide might cause inflammation, another suppress it, another stimulate cell growth, and still another instruct immune cells to migrate

Conjugation reactions such as glucuronidation and sulfation, subsequently prevent re-oxidation of the alcohol back to its parent aldehyde (181)