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In support of this observation, over expression of GS in a yeast model failed to increase GSH levels, whereas overexpression of GCL did [18]

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10,11 Notably, no serious AEs occurred in add-on trial

However, it has been reported that bortezomib reduces NFB activity and induces the unfolded protein response, ER stress and immune sensitization [113]

Thongsepee N, Martviset P, Chantree P, Sornchuer P, Sangpairoj K, Prathaphan P, Ruangtong J, Hiranyachattada S (2022) Daily consumption of monosodium glutamate pronounced hypertension and altered renal excretory function in normotensive and hypertensive rats