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Manassas, VA, USA) were seeded at a density of 2 10 3 cells per well in 96-well plates, cultured with standard culture media [DMEM, 4.5 g/L glucose, L-glutamine, sodium pyruvate (Mediatech Inc

This finding indicated that the Trp prototrophy inhibited V-ATPase-dependent autophagy via Trp and/or its derivative metabolites

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Other causes include gastrectomy, Crohn's disease, celiac disease, bariatric surgery, and chronic use of certain medications, such as proton pump inhibitors (PPIs) and metformin

Nicotinamide N-methyltransferase: metabolic regulator and emerging therapeutic target (2024 review)