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Two of these patients wanted to continue the treatment because of the significant decrease of the crisis duration and/or severity

The central role of sertoli cells in spermatogenesis

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However, it has been shown that mortality is significantly decreased by the administration of NAC even up to 36 h after the toxic ingestion and that this cohort of patients is less likely to progress to grade III/IV hepatic coma after receiving treatment with NAC[69]

Routine inflammatory marker testing is not recommended as part of standard tirzepatide therapy