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More recently, a ratiometric fluorescence nanosensor (Golgi-Zn) with high sensitivity, selectivity and robust pH stability enabled the quantitative monitoring of zinc in the Golgi, revealing that nanoplastics exposure increases Golgi zinc levels and links zinc homeostasis to nanoplastic-induced stress 192

In fact, the Cu 2+ -histidine interaction (binding) in nature can match the importance of iron (Fe 2+ ) binding with proteins, and the consequent haem interactions that support the very existence of life (Walton et al., 2023)

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Glutathione inhibits tyrosinase and shifts melanin synthesis toward light pheomelanin rather than dark eumelanin

Pharmacological targeting of the transcription factor Nrf2 at the basal ganglia provides disease modifying therapy for experimental parkinsonism