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This complex recognizes and binds to the xenobiotic response elements (XRE/DRE) in the promoter regions of target genes, subsequently initiating transcription (Post et al., 2025

438 Theophylline, a Phosphodiesterase 4 (PDE4) inhibitor, is another drug that promotes apoptosis by reducing the anti-apoptotic protein Bcl-2, which inhibits neutrophils and eosinophils in vitro

Immediate intramuscular (IM) administration into the mid-anterolateral thigh provides rapid absorption and remains the recommended route of delivery