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Adding any factor that might theoretically accelerate this progression seems unwise

TP53 mutations TP53 mutations occur in approximately 50% of NSCLC cases and are associated with aggressive tumor behavior and poor prognosis

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Coumarins, secondary antimetabolites of plants, possess antitumorigenic functions such as blocking the cell cycle, promoting cell death, inhibiting DNA topoisomerase, and modulating estrogen receptors (ER) [90]