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In contrast, activation of other cytosolic pathways during Mtb infection, such as that mediated by AIM2, NOD2, and NLRP3, can promote the production of protective inflammatory cytokines

reference to an aryl group or moiety implicitly includes both substituted and unsubstituted variants

doi: 10.1136/ard.50.10.685 133 JayaprakashKDemirelIKhalafHBengtssonT

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Additionally, in spite of their phenotypic resemblance, the underlying aging drivers between genetically manipulated progeria and naturally aged animals may be different